NURS 617 Pharm Exam 1 Summer -Jean

NURS 617 Pharm (Exam 1) Summer -Jean Genzale Latest Update - 250 Questions and 100% Verified Correct Answers Guaranteed A+ Approved by the Professor

• A 42 y / o woman is diagnosed with bacteremia in the ED . The NP empirically starts

antibiotics and want the first dose of Vancomycin to be given prior to admission to the floor . The hospital has a vancomycin nomogram for 15 mg / kg initial dosing ( rounded to the nearest 250 mg ) , followed by pharmacy dosing / pharmacokinetic service . If the patient weighs 154 pounds , what dose of vancomycin would the patient receive in the ED ? Please give your answer as a whole number without units . - CORRECT

ANSWER: 1000

• In regard to pharmacodynamics , " affinity " can be defined as : CHOOSE ONE

ANSWER

a . The measure of how tightly a drug binds to plasma proteins b . The amount of time that a measurable drug effect persists c . The degree of attraction between a drug and its receptor

d . The measure of a drug's bioavailability - CORRECT ANSWER: c . The degree of

attraction between a drug and its receptor

• Antagonist drugs prevent the actions of the body's endogenous biomediators on their

receptors by which mechanism ? CHOOSE ONE ANSWER a . Preventing agonist drugs from binding to antagonist drug b . Binding to the receptor and activating it c . Preventing occupancy of the receptor d . Mimicking the actions of the body's endogenous biomediators - CORRECT

ANSWER: c . Preventing occupancy of the receptor

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• Which of the following medications can be used for the treatment of depression ,

insomnia , and migraines ?a . SSRIs b . MAOIS c . TCAs

d . SNRIS - CORRECT ANSWER: c . TCAs

• Which of the following is an example of a graded drug response ? CHOOSE ONE

ANSWER

a . Blood pressure b . Death c . Rash

d . Sleep - CORRECT ANSWER: a . Blood pressure

A child who presents with a diagnosis of chlamydial pneumonia should be prescribed which of the following antimicrobials a . High dose amoxicillin ( Amoxil) b . Amoxicillin + clavulanate (augmentin )

• Ceftriaxone ( rocephin )

d . Macrolide - CORRECT ANSWER: d . Macrolide

A combination of hydralazine and isorbide dinitrate has been shown to be beneficial in heart failure patients who are

• African American

b . Unable to tolerate an ACE inhibitor

• > 65 years old

d . NYHA class II - CORRECT ANSWER: a. African American

A common adverse drug reaction from ACE inhibitors prescribed in the setting of heart failure is 2 / 4

a . Reflex tachycardia b Exacerbation of lower extremity edema c . Hyperkalemia d . Elevation of serum glucose in diabetics . - CORRECT ANSWER: c . Hyperkalemia

A disadvantage of the antihistamine diphenhydramine ( Benadryl ) is a . May cause bradycardia b . Only available by the oral route c . May cause urinary retention in men with prostate problems

d . Commonly causes diarrhea - CORRECT ANSWER: c . May cause urinary retention

in men with prostate problems

A disadvantage to the use of nicotinic acid ( niacin ) for hyperlipidemia is a . It will decrease the absorption of other oral drugs given simultaneously b . It is associated with constipation c . It commonly produces flushing in the face and neck area d . It may cause a life - threatening myopathy - CORRECT ANSWER: c . It commonly produces flushing in the face and neck area

A drug's therapeutic index can be defined as a . The drug dosage that produces 100 % of the therapeutic effect b . The ratio of the average lethal dose of the drug compared to the average effective therapeutic dose of the drug c . A measurement of a drugs safety and toxicity

d . The time course of a drugs action - CORRECT ANSWER: b . The ratio of the

average lethal dose of the drug compared to the average effective therapeutic dose of the drug c . A measurement of a drugs safety and toxicity

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A middle - aged executive who experienced insomnia with 2 different SSRIs . Which alternative therapy could relieve insomnia and depression ?a . MAOI b . SNRI c . TCA

d . Benzodiazepine - CORRECT ANSWER: c . TCA

A new drug seeking FDA approval has been studied in pregnant rats , rabbits , and mice and causes birth defects in these fetal animals . There are , however , no studies of this drug in pregnant women . To which pregnancy risk category does this drug belong ?a . A b . B c . C

d . D - CORRECT ANSWER: c. C

A patient presenting to the ER in status epilepticus without IV access can be treated with a . Fosphenytoin ( cerebyx ) b . Carbamazepine ( tegretol ) c . Lamotrigine ( Lamictal )

d . Phenytoin ( Dilantin ) - CORRECT ANSWER: LOOK UP

A patient who took an osmotic laxative on a daily basis could develop this as a consequence a . An impaction b . Dehydration

• Hyperglycemia

d . Hyperkalemia - CORRECT ANSWER: b . Dehydration

A patient with phenytoin may exhibit drug toxicity when concurrently taking

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