Practitioner AGPCNP Certification Exam

Adult-Gerontology Primary Care Nurse Practitioner (AGPCNP) Certification Exam Practice Test Questions And Correct Answers (Verified Answers) Plus Rationales 2026 Q&A | Instant Download Pdf

• A 68-year-old male presents with exertional chest pain relieved by rest.

Which is the most likely diagnosis?

• Gastroesophageal reflux disease
• Stable angina pectoris
• Unstable angina
• Myocardial infarction

Rationale: Stable angina presents with predictable chest pain on exertion

relieved by rest or nitroglycerin.

• Which of the following is the most appropriate first-line treatment for

isolated systolic hypertension in older adults?

• Beta-blocker 1 / 4

• Alpha-blocker
• Thiazide diuretic
• Loop diuretic

Rationale: Thiazide diuretics are first-line agents for isolated systolic

hypertension due to proven cardiovascular benefit.

• A 75-year-old woman with type 2 diabetes reports dizziness when

standing. What is the most likely cause?

• Hypoglycemia
• Orthostatic hypotension
• Stroke
• Dehydration

Rationale: Older adults with diabetes often develop autonomic

neuropathy, leading to orthostatic hypotension.

• Which of the following findings is consistent with Alzheimer’s disease?
• Sudden onset of memory loss
• Gradual decline in memory and executive function
• Fluctuating cognition and alertness
• Visual hallucinations

Rationale: Alzheimer’s disease is characterized by progressive and gradual

cognitive decline. 2 / 4

• Which immunization should be given to all adults aged 65 and older if not

previously administered?

• MMR vaccine
• Hepatitis A vaccine
• Pneumococcal conjugate vaccine
• Varicella vaccine

Rationale: Pneumococcal vaccination is recommended for adults ≥65 years

to prevent pneumonia and bacteremia.

• A 60-year-old man presents with a productive cough for 3 months each

year for the last 3 years. What is the likely diagnosis?

• Chronic bronchitis
• Emphysema
• Asthma
• Bronchiectasis

Rationale: Chronic bronchitis is defined as productive cough for at least 3

months in 2 consecutive years.

• The most appropriate screening test for colorectal cancer in a 65-year-old

man with no prior screening is:

• Sigmoidoscopy every 5 years 3 / 4

• Colonoscopy every 10 years
• CT colonography every 3 years
• Annual fecal occult blood test only

Rationale: Colonoscopy every 10 years is the preferred gold standard for

colorectal cancer screening.

• Which medication should be avoided in older adults due to risk of

delirium?

• Lisinopril
• Diphenhydramine
• Metformin
• Amlodipine

Rationale: Diphenhydramine, an anticholinergic, increases the risk of

confusion and falls in older adults.

• A 70-year-old woman presents with a new, painless thyroid nodule. What

is the most appropriate next step?

• Start levothyroxine
• Repeat thyroid exam in 6 months
• Order thyroid ultrasound with fine-needle aspiration
• Start antibiotics

Rationale: Evaluation of a thyroid nodule in older adults should include

ultrasound and biopsy to rule out malignancy.

• / 4