Psychopharm MSN 634 Exam Actual Exam

1 Psychopharm MSN 634 Exam/ Actual Exam Questions with Correct Detailed Answers (Verified) Latest .

A precursor substance from which both dopamine and norepinephrine are synthesized through enzymatic action

Select one:

• Dopamine
• Tyrosine
• Trazodone
• Serotonin - Correct Answer - b. Tyrosine

Tyrosine is a precursor element necessary for the synthesis of both norepinephrine and dopamine. For serotonin the precursor necessary is tryptophan

A precursor substance from which serotonin is synthesized through enzymatic action in the neuron

Select one:

• Glycine
• Tryptophan
• Trazodone
• Tyrosine - Correct Answer - b. Tryptophan

Tryptophan is the precursor to serotonin 1 / 4

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Which of the following statements about the heritability of major depressive disorder MDD) is true?

Select one:

• Nearly 100% of people with genetic liability can be accounted for by the personality

trait of dogmatism

• Nearly 50% of people with genetic liability can be accounted for by the personality

trait of aggressiveness.

• The heritability is approximately 40% and the personality trait of neuroticism accounts

for a substantial portion of this genetic liability

• The heritability of MDD depends on whether the individual's mother or father had

MDD

• Less than 10% of people with genetic liability can be accounted for by the personality

trait of perfectionism. - Correct Answer - c. The heritability is approximately 40% and the personality trait of neuroticism accounts for a substantial portion of this genetic liability

First-degree family members of individuals with major depressive disorder have a risk of major disorder two- to fourfold higher than that of the general population. Relative risks appear to be higher for early-onset and recurrent forms. Heritability is approximately 40%, and the personality trait neuroticism accounts for a substantial portion of this genetic liability. Neuroticism (negative affectivity) is a well-established risk factor for the onset of major depressive disorder, and high levels appear to render individuals more likely to develop depressive episodes in response to stressful life events. (166)

A 39-year-old woman reports that she became quite depressed in the winter last year when her company closed for the season, but she felt completely normal in the spring.She recalls experiencing several other episodes of depression over the past 5 years (for which she cannot identify a seasonal pattern) that would have met criteria for major depressive disorder. Which of the following correctly summarizes this patient's eligibility for a diagnosis of 'major depressive disorder, with seasonal pattern'?

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Select one:

• She does qualify for the diagnosis: the single episode started in the winter and ended

in the spring.

b. She does qualify for this diagnosis: the symptoms described are related to

psychosocial stressors

• She does not qualify for this diagnosis: the episode must start in the fall, and the

patient must have no episodes that do not have a seasonal pattern

• She does qualify for this diagnosis: the symptom - Correct Answer - E. She does not

qualify for this diagnosis: the patient must have had two episodes with a seasonal relationship in the past 2 years and no non-seasonal episodes during that period

-The 'with seasonal pattern' specifier requires a regular temporal relationship between the onset of major depressive episodes (MDEs) in major depressive disorder or in bipolar I or bipolar II disorder and a particular time of the year (e.g., in the fall or winter.The diagnosis excludes cases in which there is an obvious effect of seasonal-related psychosocial stressors (e.g., regularly being unemployed every winter.) Full remissions (or a change from major depression to mania or hypomania) also occur at a characteristic time of the years (e.g., depression disappears in the spring). In the past 2 years, two MDEs must have occurred that demonstrate the temporal seasonal relationships defined above, and no non-seasonal MDEs must have occurred during that same time. Seasonal MDEs must substantially outnumber the non-seasonal MDEs that may have occurred over the individual's lifetime. The specifier 'with seasonal pattern' can be applied to the pattern of MDEs in bipolar I disorder, bipolar II disorder, or major depressive disorder, recurrent.

What is the appropriate method of confirming a diagnosis of premenstrual dysphoric disorder?

Select one:

• Two or more months of prospective symptom ratings on validated scales
• Family history
• Neuropsychological testing
• One month of scoring high on the Daily Rating of Severity of Problems or 1 month of

scoring high on the Visual Analogue Scales for Premenstrual Mood Symptoms.

• Laboratory tests - Correct Answer - a. Two or more months of prospective symptom

ratings on validated scales 3 / 4

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-The diagnosis of premenstrual dysphoric disorder is appropriately confirmed by 2

months of prospective symptom ratings. (Note: The diagnosis may be made

provisionally prior to this confirmation.) A number of scales, including the Daily Rating of Severity of Problems or the Visual Analogue Scales for Premenstrual Mood Symptoms have undergone validation and are commonly used in clinical trials for premenstrual dysphoric disorder. The Premenstrual Tension Syndrome Rating Scale has a self-report and an observer version, both of which have been validated and used widely to measure illness severity in women who have premenstrual dysphoric disorder. (173- 174)

A client whose hypertension is well-controlled on clonidine presents with major depression. Which of the following antidepressants should be avoided in the treatment of his depression?

Select one:

• Fluoxetine
• Paroxetine
• Nortriptyline
• Bupropion - Correct Answer - c. Nortriptyline

Nortriptyline when administered with clonidine may result in hypertension because the combination decreases the effects of clonidine. No drug-to-drug of clonidine has been reported with paroxetine, fluoxetine, or bupropion.

Children with disruptive mood dysregulation disorder (DMDD) often meet criteria for what additional DSM-5 diagnosis?

Select one:

• Pediatric bipolar disorder
• Major depressive disorder
• Intermittent explosive disorder
• Schizophrenia
• Oppositional defiant disorder - Correct Answer - e. Oppositional defiant disorder
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