Psychopharm N358 Exam Actual Exam Questions

1 Psychopharm N358 Exam/ Actual Exam Questions with 100% Verified Answers/ Latest Update - Rated A+

what is methadone - ANSWER - opioid agonist, synthetic narcotic analgesic

what is methadone used for - ANSWER - substitution or opioid maintenance therapy

why is methadone used - ANSWER - harm-reduction strategy to reduce associate risks of heroin or IV drug use (infectious diseases), reduce or prevent other negative consequences of illicit substance use (crime and violence)

methadone may contribute to - ANSWER - increased psychosocial stability

buprenorphine class - ANSWER - partial opioid agonist Subutex

properties of buprenorphine - ANSWER - some agonist and some antagonist

buprenorphine causes decreased - ANSWER - subjective euphoria and abuse potential

buprenorphine has extremely high - ANSWER - binding capacity to opioid receptors

dietary restrictions which which MAOI may not be necessary - ANSWER - selegeline transdermal system (Emsam) at 6mg/24 hour modifications recommended at 9mg and 12mg/24 hour 1 / 3

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tricyclic antidepressants may also be used for treatment of - ANSWER - chronic pain

What is different about tricyclic antidepressants from SSRIs? - ANSWER - more pronounced side effects and safety considerations

side effects of tricyclic antidepressants - ANSWER - anticholinergic effects (dry mouth, constipation) orthostatic hypotension photosensitivity (eyes and skin) risk of potentially fatal overdose in suicide attempts

tricyclic antidepressant examples - ANSWER - amitryptiline imipramine (Tofranil) clomipramine (Anafranil) effective in treatment of OCD

what kind of side effect profiles do SSRIs and SNRIs have - ANSWER - benign, safer

when will therapeutic response with SSRIs and SNRIs occur - ANSWER - a few weeks to a few months

characteristics of sertraline - ANSWER - Zoloft - SSRI, among most commonly prescribed what can occur when duloxetine is discontinued abruptly? - ANSWER - discontinuation syndrome, like the flu

which antidepressant class is the treatment of choice for long-term management of anxiety disorders - ANSWER - SSRIs and SNRIs

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3 SSRI and SNRI initial dosing - ANSWER - start low and go slow to avoid initial worsening of symptoms start at half or less recommended dose

interruption in SSRI and SNRI regimen or abrupt termination may result in - ANSWER - discontinuation syndrome with flu like symptoms

What puts someone at risk for serotonin syndrome - ANSWER - two or more medications and/or illicit agents that potentiate serotonergic neurotransmission (St.John's Wort and ecstasy)

symptoms of serotonin syndrome - ANSWER - changes in mental status, restlessness, elevated temperature, tachycardia, labile blood pressure, diaphoresis, shivering, tremors

treatment for serotonin syndrome - ANSWER - cyproheptadine (Periactin) - histamine 1 receptor antagonist and supportive measures

examples of heterocyclic antidepressants - ANSWER - bupropion (Wellbutrin) miratazapine (Remeron) trazodone (Desyrel)

characteristics of fluoxetine - ANSWER - Prozac - SSRI, longer half-life

characteristics of fluvoxamine - ANSWER - Luvox - SSRI, may be used to treat OCD

characteristics of citalopram - ANSWER - Celexa - SSRI, obtain baseline EKG, not dosed higher than 40mg/day because of cardiac effects

characteristics of duloxetine - ANSWER - Cymbalta - SNRI, depression and/or pain

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