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Anti-neoplastic drugs
By: Muhammad Aurangzeb
Lecturer-INS/KMU
Objectives
By the end of this unit, students will be able to:
•Review the characteristics of normal and malignant cells.•Explain characteristics of anti-neoplastic drugs.•Classify anti-neoplastic drugs.•Discuss the nursing care of patients who are on anti-neoplastic drugs.•Calculate the drug dosage for Anti-neoplastic drugs.
Introduction •Normal cells… •Differentiate, grow, mature, divide –Regulated, balanced; cell birth=cell death
•Regulation: intracell signaling
–Hyperplasia: new cells production with growth stimulus via hormones,
endogenous signals
•Ex: hyperplasia of endometrial tissue during menstrual cycle is normal
and necessary –BUT if intense, prolonged demand •May cell structural, functional abnormalities
•– Metaplasia:replacement of one cell type by another
Introduction
–Dysplasia:replacement cells are disordered in
size, shape •Increased mitosis rate •Somewhat reversible, often precancerous
–Neoplasia:abnormal growth/invasion of cells
•“New growth” •Neoplasm = tumor •Irreversible •Cells replicate, grow with /out control
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