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Unit-VI C Thyroid and Anti-Thyroid Drugs
By: Muhammad Aurangzeb
Lecturer-INS/KMU
Objectives
By the completion of this section the learners will be able to:
•Review the physiologic effects of thyroid hormone.•Identify effects of hypo and hyper secretions of thyroid hormone.•Discuss actions, indications, side effects of thyroid and anti- thyroid drugs.•Integrate the influence of thyroid and anti-thyroid drugs on the metabolism of other drugs.•Calculate drug dosages accurately.
Thyroid Gland •Thyroid is an endocrine gland. It has two lobes, which are connected in the middle by an isthmus.•Thyroid gland facilitates normal growth and maturation by maintaining a level of metabolism in the tissues that is optimal for their normal function.
•Thyroid gland secretes three hormones:
- Tetraiodothyronine or T4 (thyroxine)
- Tri-iodothyronine or T3
- Calcitonin
•T4 is otherwise known as thyroxine and it forms about 80% of the total secretion, whereas T3 is only 20%.Hormones of thyroid gland
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