Saunders’ Comprehensive NCLEX - RN® Test Bank | 2025/2026 Latest Edition Real Exam-Based Questions and Verified Rationalized Answers | 100% Accuracy | NCLEX-RN® Mastery Resource | Graded A+ Introduction This resource includes 200 verified NCLEX-RN® multiple-choice questions and correct answers with detailed rationales, sourced from the trusted Saunders’ Comprehensive Review. Fully aligned with the 2025/2026 NCLEX-RN® Test Plan, it focuses on key categories such as Safe and Effective Care Environment, Health Promotion and Maintenance, Psychosocial Integrity, and Physiological Integrity.Answer Format All correct answers are clearly marked in bold and green, each supported with rationales to build critical thinking and testing confidence.
Questions
- A nurse is caring for a patient receiving heparin therapy for a
pulmonary embolism. Which laboratory value should the nurse monitor closely?
a) International Normalized Ratio (INR)
b) Activated partial thromboplastin time (aPTT)
c) Platelet count
d) Hemoglobin A1c
b) Activated partial thromboplastin time (aPTT)
Rationale: Heparin is monitored using aPTT to ensure therapeutic anticoagulation and prevent bleeding or clotting complications.
- A patient is to receive 1000 mL of normal saline over 8 hours. What is
- 100 mL/hr 1 / 4
the IV flow rate in mL/hr?
- 125 mL/hr
- 150 mL/hr
- 175 mL/hr
- 125 mL/hr
Rationale: 1000 mL ÷ 8 hours = 125 mL/hr.
- A nurse is caring for a patient with a new diagnosis of type 1 diabetes.
Which symptom should the nurse expect?
a) Weight gain
b) Polyuria
c) Bradycardia
d) Constipation
b) Polyuria
Rationale: Polyuria is a classic symptom of type 1 diabetes due to hyperglycemia-induced osmotic diuresis.
- A patient is prescribed 600 mg of ibuprofen PO. The tablets are 200
- 1 tablet
- 2 tablets
- 3 tablets
- 4 tablets
- 3 tablets
mg each. How many tablets should the nurse administer?
Rationale: 600 mg ÷ 200 mg/tablet = 3 tablets.
- A nurse is preparing to administer a blood transfusion. Which action
is most important before starting the transfusion?
a) Checking the patient’s temperature
b) Verifying the blood type with another nurse
c) Administering an antihistamine
d) Flushing the IV line with D5W
b) Verifying the blood type with another nurse
Rationale: Verifying the blood type with another nurse prevents transfusion reactions due to mismatched blood. 2 / 4
- A patient with a history of heart failure reports dyspnea when lying
flat. What is the nurse’s best action?
a) Place the patient in a supine position
b) Elevate the head of the bed
c) Administer a bronchodilator
d) Restrict fluid intake
b) Elevate the head of the bed
Rationale: Elevating the head of the bed relieves orthopnea, a common symptom of heart failure.
- A patient is to receive 0.5 mg of lorazepam IV. The vial contains 2
- 0.25 mL
- 0.5 mL
- 1 mL
- 1.5 mL
- 0.25 mL
mg/mL. How many mL should the nurse administer?
Rationale: 0.5 mg ÷ 2 mg/mL = 0.25 mL.
- A nurse is caring for a patient with a suspected myocardial infarction.
Which diagnostic test is most specific?
a) Chest X-ray
b) Troponin levels
c) Complete blood count
d) Blood glucose test
b) Troponin levels
Rationale: Troponin levels are highly specific for myocardial injury, indicating a myocardial infarction.
- A patient with a history of seizures suddenly begins to convulse. What
is the nurse’s priority action?
a) Administer lorazepam IV
b) Ensure patient safety by clearing the area
c) Restrain the patient to prevent injury
d) Insert an oral airway 3 / 4
b) Ensure patient safety by clearing the area
Rationale: Protecting the patient from injury during a seizure by clearing hazards is the priority.
- A patient is to receive 500 mL of lactated Ringer’s over 4 hours. The
- 30 gtt/min
- 31 gtt/min
- 32 gtt/min
- 33 gtt/min
- 31 gtt/min
- A nurse is teaching a patient with asthma about using a metered-dose
IV tubing has a drop factor of 15 gtt/mL. What is the flow rate in gtt/min?
Rationale: 500 mL ÷ 4 hours = 125 mL/hr. 125 mL/hr ÷ 60 min ≈ 2.083 mL/min. 2.083 mL/min × 15 gtt/mL ≈ 31 gtt/min.
inhaler (MDI). Which instruction is most important?
a) Inhale the medication quickly
b) Shake the inhaler well before use
c) Hold the inhaler 6 inches from the mouth
d) Use the inhaler every 2 hours
b) Shake the inhaler well before use
Rationale: Shaking the inhaler ensures proper mixing of the medication for effective delivery.
- A patient with a history of chronic kidney disease reports nausea and
fatigue. Which laboratory value should the nurse monitor?
a) Blood glucose
b) Creatinine
c) Sodium
d) Hemoglobin
b) Creatinine
Rationale: Creatinine levels reflect kidney function, critical in chronic kidney disease.
- A patient is prescribed 25 mg of diphenhydramine IV. The vial
- / 4
contains 50 mg/mL. How many mL should the nurse administer?