UNIT 9 MN 553 Pharm Latest Update -

UNIT 9 MN 553 Pharm Latest Update - Actual Exam Questions and 100% Verified Correct Answers Guaranteed A+

A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is

inactivated by the body may lead to:

Question options:

Decreased effectiveness of irinotecan in the treatment of cancer

Increased adverse drug reactions, such as neutropenia

Delayed metabolism of the prodrug irinotecan into the active metabolite SN-38

Increased concerns for irinotecan being carcinogenic - CORRECT ANSWER: Increased adverse drug reactions, such as neutropenia

A good history of herb and supplement use is critical before prescribing because approximately ____ % of patients in the United States are using herbal products.

Question options:

10

5

38

70 - CORRECT ANSWER: 38

• / 3

A potential harmful effect on patients who take some herbal medication is:

Question options:

Constipation

Lead poisoning

Diarrhea

Life-threatening rash - CORRECT ANSWER: Lead poisoning

A thorough understanding of herbs is critical to patient safety. An example is the use of cinnamon to treat type II diabetes. It is important the patient uses Ceylon cinnamon, as

the commercially available cassia cinnamon contains:

Question options:

Coumadin, which may lead to bleeding problems

Coumarin, which can cause liver and kidney damage

Cinnamic aldehyde, which is toxic to the kidney

Cinnamate eugenol, which is toxic to the liver - CORRECT ANSWER: Coumarin, which can cause liver and kidney damage

According to traditional Chinese medicine, if a person who has a fever is given a herb

that is yang in nature, such as golden seal, the patient's illness will:

Question options:

Get worse 2 / 3

Get better

Not be adequately treated

Need additional herbs to treat the yang - CORRECT ANSWER: Get worse

As drugs near the end of their patent, pharmaceutical companies may apply for the drug

to change to over-the-counter status in order to:

Question options:

Get a new patent for the over-the-counter form of the drug

Lower the costs because most prescription benefit plans do not cover generics

Market the drug to a whole new population, as they are able to market to patients instead of just providers

Continue to make large profits from their blockbuster brand-name drug - CORRECT

ANSWER: Continue to make large profits from their blockbuster brand-name drug

Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502

allele in patients with Asian ancestry prior to starting therapy due to:

Question options:

Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele

Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele

• / 3