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USMLE latest exam questions and answers 2025/2026 |100% correct An infant is born prematurely to a 34 yearold female. Physical examination reveals of clenching of the left hand with the 5th finger overriding the 4th finger. The infant also has a small jaw and excessive pedal tissue. This can be best explained by which of the following inherited lesion? - ANSWER- Trisomy 18 Edward syndrome
A 33 y/p has history of Charcot-Marie tooth diseas. She is experiencing progressive difficulties in her breathing as well as myriad of GI problems. If she experience musculoskeletal complication as her disease progresses which of the following areas is like negatively affected? - ANSWER-Hip joints
A 38 year old male is being treated for a major depressive disorder with Fluoxetine. 3 weeks into treatment he is experiencing recurring erectile dysfuction? Which function of the following medication is most needed for him at this point? - ANSWER-Bupropion
A 19 year old male is being held for 72 hours observation because of recent spending spree that he went on using his parent's credit cards. He was being treated for signs and symptoms of depression with Fluxetine, and once he began feeling better, he began to spend money and drive recklessly. his findings are most strongly associated with which of the following?
- Decreased NE, Decreased 5-HT, Decreased DA
- Increased DNA
- Decreased Ach, Increased Glutamate
- Decreased 5-TH, Decreased NE, Decreased GABA
- Increased 5-TH, Increased DA, Decreased Glutamate - ANSWER-Increased DNA
66 year old male maxillofacial surgeon is having relationship difficulties with his wife. While performing a left sided facial reconstruction, the nurse assistant fumbles a cotton ball and is yelled at excessively. The surgeon continues to berate the nurse for the next 30 minutes. This is an example of which of the following.
- Isolation of affect
- Projection
- Dissociation
- Altruism
- Displacement - ANSWER-Displacement 1 / 2
24 year old construction worker is seeking help for feeling of sadness, guilt, anhedonia, and loss of interest in life. A full physical work up and psychological evaluation is performed. His urinary levels of 3-methoxy-4-hydroxyphenylglycol are found to be much lower than normal. He tells you he has considered suicide but does not have a plan in place. Which of the following enzymes is responsible for the production of nuerotransmitter that is deficient in this patient?
- Tryptophan hydroxylase
- Dopamine beta-hydroxylase
- Tyrosine hydroxylase
- Glutamate decarboxylase
- Phenylethanolamine-N-methyltransferase - ANSWER-Dopamine Beta Hydroxylase
26 year old married mother of tow is seeing you six weeks after she was started on Fluoxtine for her depression. She is shy about bringing up her recent lack of sexual desire for her husband, but decides to share her concerns with you. Further explanation reveals that her relationship is good, however she has no desire for sex with her husband. At this point, switching her to which of the following will be an ideal in helping alleviate her sexual side effects?
- Buspirone
- Balcofen
- Buproprion
- Paroxetine
- Prochlorperazine - ANSWER-Buproprion
24 year old male is being escorted into the ER by five policeman after punching through a brick wall outside of a downtown nightclub. Police required to a tazer gun in order to arrest him. He is belligerent and is immediately injected with Haloperidol in order to calm him down. He is most likely under the influence of which of the following?
- Lysergic acid diethylamide
- Marijuana
- Phencyclidine
- Cocaine
- Ketamine - ANSWER-Phencyclidine
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