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UTMB ADVANCED PATHOPHYSIOLOGY
5355 EXAM 3
EXAM WITH CORRECT SOLUTIONS.
Biogenic Amine Theory linked to depression - correct answer- Deficiency of neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin. Particularly, a decrease in receptor binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression - correct answer- A deficiency of monoamine neurotransmitters at neuronal synapses.
Antidepressants increase - correct answer- Neuronal synaptic levels of monoamine neurotransmitters.
if you have more receptors than neurotransmitters - correct answer- Neurotransmitters do not have time to re-charge thus, they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation - correct answer- HPA system dysregulation with excessive 1 / 3
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glucocorticoid secretion is found in a large percentage of people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of -- , with decreased levels of - - correct answer- Amyloid B, neurofibrillary tangles, acetylcholine these disrupt impulse transmission
neurofibrillary tangles - correct answer- are a deformation of the structure that carries nutrients to neurons of the brain.
Decreased levels of choline acetyl transferase and acetylcholine is associated with - correct answer- Memory loss
Most common cause of dementia - correct answer- Alzheimer's disease fatal 5-10 years
Characteristics of Alzheimer's - correct answer- Loss of memory, language , inability to learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects social life
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Parkinson's Disease is - correct answer- Chronic motor progressive neuro-degenerative known as a shaking palsy
Parkinson's disease is associated with - correct answer- basal ganglia dysfunction and atrophy of neurons in the substantia nigra that produce dopamine;
Characteristics of Parkinson's disease - correct answer- Tremors at rest, rigidity, bradykinesia, muscular rigidity and postural abnormalities.
- Main Categories of CVA - correct answer- Hemorrhagic and
Ischemic
Hemorrhagic CVA - correct answer- Blood produces inflammatory reaction, swelling, displaces brain tissue and increases ICP
- types of hemorrhagic stroke - correct answer- Intracerebral
and subarachnoid
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