Week 2 Midterm Exam: NR546 NR-

Week 2 Midterm Exam: NR546 / NR-

546 (Latest 2025 / 2026) Advanced Pharmacology Psychopharmacology for the PMHNP | Questions and Answers | 100% Correct | Grade A - Chamberlain

Question:

What influences drug metabolism

Answer:

age, smoking, caffeine, other mediation/polypharmacy, nicotine

Question:

How are medication effected with poor metabolizers

Answer:

poor metabolizers have lower concentrations of the enzymes needed to metabolize drugs. Therefore, they would have higher blood concentration, elevated drug levels and increased risk of drug-drug reaction, risk for drug toxicity

• / 3

Question:

How are medication effected with rapid metabolizers

Answer:

elevated enzyme activity breaks the drug down faster and causes subtherapeutic drug levels- need higher doses for drug to be effective •

Question:

Most drug doses are set at values for what type of metabolizer

Answer:

extensive

Question:

Signal transduction cascades

Answer:

Signal transduction cascades can produce downstream (delayed) and/or long- lasting effects, which explains why some psychopharmacological drugs do not provide an immediate response but require time to see the drug effects.

• / 3

Question:

How are drug blood concentration affected with poor metabolizers

Answer:

Poor metabolizers have a lower concentration of the necessary enzyme which results in higher blood concentrations of the drug.

Question:

g-linked protein

Answer:

Is triggered by a NTM. Passes messages from one receptor to another. the second messenger is a chemical; once bound to enzyme it changes shape

Question:

most comon inhibitory NTM in the spinal cord

Answer:

glycine

Question:

What is the theory of how psychotropic medication work

Answer:

psychotropic mediation impact NTM by either enhancing or decreasing the NTM ability to bind to receptor sites

• / 3