Week 6 Final Exam: NR546 NR-546

Week 6 Final Exam: NR546 / NR-546

(Latest 2025 / 2026) Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner | Test Questions and Answers | 100% Correct | Grade A - Chamberlain

Question:

Disulfiram (Antabuse)

Answer:

Abstinence maintenance med of alcohol

Question:

Disulfiram teaching/testing

Answer:

PRIOR TESTS -Baseline and follow-up liver function tests EDUCATION - patient should not take until at least 12 hours after drinking classic drug for treating alcoholism -irreversible inhibitor of the liver enzyme aldehyde dehydrogenase that normally metabolizes alcohol 1 / 3

-alcohol ingested with disulfiram, alcohol's metabolism is inhibited, build-up of toxic levels of acetaldehyde, creates an aversive experience with flushing, nausea, vomiting, and hypotension.-compliance is a problem

Question:

Impulsivity and compulsivity are thought to be mediated by neuroanatomically and neurochemically distinct, but in many ways parallel, components of?

Answer:

cortico-subcortical circuitry -too much "bottom-up" limbic emotional drive or too little "top-down" cortical inhibition of these drives

Question:

Impulsive-compulsive disorder construct

Answer:

-Impulsivity can be thought of as the inability to stop the initiation of actions and involves a brain circuit centered on the ventral striatum and linked to the thalamus, to the ventromedial prefrontal cortex (VMPFC), and to the anterior cingulate cortex (ACC).

Impulsive acts such as drug use, gambling, and over-eating can eventually become compulsive due to neuroplastic changes that engage the dorsal habit system and theoretically cause impulses in the ventral loop to migrate to the dorsal loop. 2 / 3

Question:

Compulsivity

Answer:

-Compulsivity can be thought of as the inability to terminate ongoing actions and hypothetically involves a brain circuit centered on the dorsal striatum and linked to the thalamus and orbitofrontal cortex (OFC).

Question:

Impulsivity circuit

Answer:

-prefrontal ventral striatal reward circuit -orbital frontal cortex

Question:

Impulsivity s/s

Answer:

• excessive talking • blurting things out • not waiting one's turn • interrupting

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