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Term:
What is the antitdote for:
Opioid analgesics, heroin
Definition:
Nalmefene, Naloxone
Term:
Digitoxin
Definition:
Therapeutic: 20-35 ng/ml
Toxic: >45 ng/ml
Contraindicated in:
Uncontrolled ventricular arrhythmias, AV block
Side Effects of Toxicity:
Abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and other arrhythmias.
Term:
What is the antitdote for:
Cyanide
Definition:
Amyl nitrite, sodium nitrite, sodium thiosulfate
Term:
Lithium
Definition:
Therapeutic: 0.6-1.2 mcg/ml
Toxic: >2 mcg/ml
Serum levels should be monitored twice weekly during initiation of therapy and every 2 to 3 months durgin chronic therapy.
Contraindicated in:
Severe cardiovascular or renal disease, dehydrated or debilitated patients
Side Effects of Toxicity:
Vomiting, diarrhea, slurred speech, decreased coordination, drowsiness, muscle weakness, and twitching.Therapeutic effects within 1 to 3 weeks of initiating therapy.
Term:
Kanamycin
Definition:
Troughs Peaks
- mcg/ml 35 mcg/ml
Term:
Streptomycin
Definition:
Troughs Peaks Varies 25 mcg/ml
Term:
Tobramycin
Definition:
Troughs Peaks
- mcg/ml 20 mcg/ml
Term:
Chlordiazepoxide (Librium)
Definition:
Therapeutic: 700-1000 mcg/ml
Toxic: >5000 mcg/ml
Contraindicated in:
Comatose patients with CNS depression, narrow-angle glaucoma
Side Effects of Toxicity:
Drowsiness and dizziness.
Alcohol Withdrawal Treatment:
Assess patients for signs and symptoms of delirium tremors (DTs).
Term:
Lidocaine (Xylocaine)
Definition:
Therapeutic: 1.5-6 mcg/ml
Toxic: >6-8 mcg/ml
Contraindicated in:
Advanced AV block
Side Effects of Toxicity:
Confusion, excitation, blurred or double vision, nausea, vomiting, ringing in ears, tremors, twitching, convulsion, difficulty breathing, severe dizziness or fainting, and slow heart rate.
Term:
Theophylline
Definition:
Therapeutic: 10-20 mcg/ml
Toxic: >20 mcg/ml
Contraindicated in:
Uncontrolled arrhythmias and hyperthyroidism
Side Effects of Toxicity:
Anorexia, nausea, vomiting, stomach cramps, diarrhea, confusion, headache, restlessness, flushing, increased urination, insomnia, tachycardia, arrhythmias, and seizures. Tachycardia, ventricular arrhythmias, or seizures may be the first sign of toxicity.
Term:
What is the antitdote for:
Acetaminophen
Definition:
Acetylcysteine
Term:
Alcohol (Ethanol)
Definition:
Therapeutic Level: 100 mcg/ml
Toxic: >400 mcg/ml
Term:
What is the antitdote for:
Tricyclic antidepressants
Definition:
Physostigmine
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