FREE BIOLOGY AND STUDY GAMES ABOUT IMMUNOLOGY

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FREE BIOLOGY AND STUDY GAMES ABOUT IMMUNOLOGY

EXAM QUESTIONS

Actual Qs and Ans Expert-Verified Explanation

This Exam contains:

-Guarantee passing score -259 Questions and Answers -format set of multiple-choice -Expert-Verified Explanation

Question 1: The only cells that possess antigen-BINDING surface molecules

Answer:

T and B

Question 2: lymphocytes

Answer:

B, plasma, Th, Tc, Memory B/T, NK

Question 3: when B cell is mature, what Igs does it display?

Answer:

membrane IgM and IgD

Question 4: complement pathway that is the third to act

Answer:

classical pathway

Question 5: the complement system consists of ___ and ___ proteins that interact with one another and with other molecules of the immune system to generate products that eliminate microbes

Answer:

serum, cell surface

Question 6: Factor that is critical for TH2 differentiation

Answer:

GATA-3

Question 7: 2 forms of antibodies

Answer:

membrane bound on the surface of B cells that function as receptors for antigen, secreted antibodies

Question 8: 1st antibody to appear in serum upon introduction to antigen

Answer:

IgM

Question 9: humoral immune response effected by

Answer:

antibodies expressed on the surface of B lymphocytes and terminally differentiated B cells called plasma cells Question 10: most ___ proteins do not contain multiple identical epitopes and are not polyvalent unless they are in ___

Answer:

globular, aggregates Question 11: CD4+ T cells that differentiate into TH2 cells secrete IL___ and IL___

Answer:

IL-4 AND IL-5

Question 12: After naive lymphocytes are activated, they become larger and proliferate, and are called

Answer:

lymphoblasts

Question 13: antibody secreting plasma cells

Answer:

effector B cells Question 14: produced by virus-infected cells in response to sensors of viral RNA, bind to receptors on neighboring uninfected cells, activate Jak-STAT pathways which induce expression of genes whose produces interfere with viral replication

Answer:

Type 1 IFNs Question 15: ability of antibodies to neutralize toxins and infectious microbes, dependent on tight binding of the antibodies

Answer:

affinity maturation Question 16: IL__, made by activated macrophages and dendritic cells, induces TH1 cell development through a ____ dependent pathway

Answer:

12, STAT4

Question 17: antibody isotope of functions: activation of the classical pathway of complement, opsonization of antigens for phagocytosis, antibody-dependent cell-mediated cytotoxicity mediated by NKs, feedback inhib of B cell activation, neonatal immunity

Answer:

IgG Question 18: __ phagocytes function as APCs in T cell mediated adaptive immune responses

Answer:

mononuclear

Question 19: antibodies found in the third fastest migrating group of globulins

Answer:

gamma globulins

Question 20: the proteolytic products ___, ___, and ___ stimulate leukocyte recruitment and inflammation

Answer:

C5a, C3a, C4a

Question 21: molecules that stimulate immune responses

Answer:

immunogens

Question 22: synthesize and secrete antibodies

Answer:

plasma cells Question 23: perforin-mediated lysis by NK cells is ___ ___ and not ____ ____, whereas Tc cells only attack cells bearing specific antigenic peptides bound to a class I MHC molecule

Answer:

antigen dependent; MHC restricted

Question 24: cytokine that is a central mediator of toxic shock syndrome

Answer:

TNF-a Question 25: all effector functions of antibodies are mediated by the binding of antigens to the

____ ____

Answer:

variable regions Question 26: bind to receptors on infected cells and induce expression of genes whose products enhance the cell's susceptibility to CTL-mediated killing

Answer:

Type I IFNs Question 27: the adaptive immune response to microbes that infect and replicate in the cytoplasm of various cell types, including nonphagocytic cells is mediated by _____ Cytotoxic T Lymphocytes, which kill infected cells

Answer:

CD8+