BIOLl 322/l BIOL322l Modulel 8:l (Latestl
2026/l 2027l Update)l 100%l Verifiedl Questionsl &l Answersl |l Gradel A
Q:l Whyl can'tl dopaminel bel administeredl asl treatmentl tol thosel withl Parkinsons?
Answer:l
Dopaminel can'tl crossl thel bloodl brainl barrier
Q:l Whatl isl thel majorl drugl treatmentl forl motorl symptomsl ofl Parkinsons?l Whatl isl thel drug?
Answer:l
Levodopal (L-DOPA)l |l intermediatel inl thel synthesisl ofl dopaminel (convertedl vial dopal decarboxylase)
Q:l Whatl isl al sidel effectl ofl L-DOPA?l (2)
Answer:l
Dyskinesiasl (involuntaryl movementsl andl tics)l andl psychosis
Q:l Whatl isl rarel medicall interventionl thatl canl helpl withl Parkinsons?
Answer:l
Deepl brainl stimulationl (DBS)
Q:l Whatl isl multiplel sclerosisl (MS)?
Answer:l
Al diseasel thatl resultsl froml thel destructionl ofl myelinl inl thel CNS 1 / 3
Q:l MSl damagesl bothl ascendingl andl descending?
Answer:l
Neurons
Q:l Whatl mightl al personl withl MSl experience?l (4)
Answer:l
1.l Musclel weaknessl andl spasms 2.l Poorl balance 3.l Numbnessl 4.l Pain
Q:l MSl canl alsol causel cognitivel impairment,l visionl lossl and?
Answer:l
Depression
Q:l MSl affectsl peoplel worldwidel andl appearsl betweenl thel agel rangel of?
Answer:l
20l -l 50l yearsl old
Q:l Isl therel al curel forl MS?l Whatl isl treatmentl gearedl towards?
Answer:l
Slowingl thel progressionl andl helpingl patientsl recoverl froml anl attack
Q:l Howl muchl onl averagel doesl MSl decreasel lifel expectancyl by?l (ofl note,l MSl isl notl necessarilyl deadly,l peoplel arel justl asl likelyl tol diel froml naturall causes)
Answer:l
5-10l years 2 / 3
Q:l Whatl isl thel leadingl theoryl onl thel causel ofl MS?
Answer:l
Al faultyl immunel systeml thatl attacksl itsl ownselfl andl targetsl myelinl forl destruction,l causingl demyelination
Q:l Whatl isl thel probleml withl immunosuppresantsl andl MS?
Answer:l
Immunosuppressionl willl putl thel personl atl riskl forl developingl anl illnessl al thatl healthyl immunel systeml wouldl fendl offl atl thel suspensel ofl haltingl MSl progression
Q:l Whatl isl Huntington'sl disease?
Answer:l
Neurodegenerativel movementl disorderl resultingl froml variousl dysfunctionall signalingl pathwaysl ofl thel basall ganglia
Q:l Whatl arel somel symptomsl ofl HD?l (3)
Answer:l
Hyperkinesial (uncontrolledl movement),l poorl coordinationl andl cognitivel changesl leadingl tol dementia
Q:l Isl therel al curel forl HD?l Whatl isl thel prognosis?
Answer:l
Nol curel forl thel diseasel |l Prognosisl isl usuallyl fatall withinl 15l yearsl ofl dx
Q:l Howl isl HDl passedl down?l Whatl proteinl isl thel culprit?
Answer:l
Autosomall dominantl mannerl |l Huntingtinl proteinl (Htt)
- / 3