Exam Practice Test Questions And

Family Nurse Practitioner Certification Exam Practice Test Questions And Correct Answers (Verified Answers) Plus Rationales 2026 Q&A | Instant Download Pdf

• A 32-year-old female presents with dysuria, frequency, and urgency.

Which organism is most commonly responsible for uncomplicated urinary tract infections?

• Staphylococcus aureus
• Escherichia coli
• Pseudomonas aeruginosa
• Enterococcus faecalis

Rationale: Escherichia coli is the most frequent cause of uncomplicated

urinary tract infections due to its uropathogenic virulence factors that allow adherence to uroepithelial cells._

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• A 45-year-old male with hypertension presents for a follow-up. Which

antihypertensive drug is preferred as first-line therapy in the absence of comorbidities?

• Beta-blocker
• Alpha-blocker
• Thiazide diuretic
• Loop diuretic

Rationale: Thiazide diuretics are recommended as first-line

antihypertensive agents for most patients with uncomplicated hypertension according to JNC 8 guidelines._

• A 68-year-old with COPD has increased sputum production and

purulence. Which antibiotic is most appropriate?

• Azithromycin
• Amoxicillin-clavulanate
• Ciprofloxacin
• Cephalexin

Rationale: Amoxicillin-clavulanate covers common COPD exacerbation

pathogens, including H. influenzae, M. catarrhalis, and S. pneumoniae._

• Which vaccine is contraindicated in pregnancy?
• Tdap

B. MMR 2 / 4

• Influenza (inactivated)
• Hepatitis B

Rationale: MMR is a live vaccine and is contraindicated in pregnancy due

to potential teratogenicity._

• A 15-year-old presents with sore throat, fever, and anterior cervical

adenopathy. Which test confirms the diagnosis of Group A streptococcal pharyngitis?

• Throat culture
• Rapid antigen detection test

C. CBC

• Monospot

Rationale: Rapid antigen detection testing (RADT) provides quick

confirmation of Group A Streptococcus infection._

• A 54-year-old woman presents with fatigue, constipation, and dry skin.

TSH is elevated, and free T4 is low. What is the diagnosis?

• Hyperthyroidism
• Primary hypothyroidism
• Secondary hypothyroidism
• Subclinical hypothyroidism

Rationale: Elevated TSH with low free T4 indicates primary hypothyroidism

due to thyroid gland failure._ 3 / 4

• A 7-year-old child has a bark-like cough, inspiratory stridor, and

hoarseness. What is the most likely diagnosis?

• Epiglottitis
• Bronchiolitis
• Croup (laryngotracheobronchitis)
• Asthma

Rationale: Croup presents with a barking cough and inspiratory stridor,

typically caused by parainfluenza virus._

• The most appropriate screening test for colorectal cancer in average-risk

adults starting at age 45 is:

• Abdominal CT scan
• Colonoscopy every 10 years
• Stool culture
• Flexible sigmoidoscopy every 3 years

Rationale: Colonoscopy every 10 years remains the gold standard for

colorectal cancer screening._

• A 26-year-old presents with lower abdominal pain, cervical motion

tenderness, and mucopurulent discharge. What is the recommended treatment?

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