Exam Questions And Correct Answers

Certified Geriatric Pharmacist Practice Exam Questions And Correct Answers (Verified Answers) Plus Rationales 2026 Q&A | Instant Download Pdf

• Which of the following medications is most commonly associated with

orthostatic hypotension in older adults?

• Lisinopril
• Clonidine
• Metoprolol
• Furosemide

Rationale: Clonidine, an alpha-2 agonist, can reduce sympathetic tone

leading to orthostatic hypotension, especially in older adults.

• Which of the following is a recommended strategy to reduce

polypharmacy in elderly patients? 1 / 4

• Increasing all medications to standard doses
• Deprescribing unnecessary medications
• Switching all oral medications to injectables
• Prescribing new medications for all comorbidities

Rationale: Deprescribing involves reviewing and discontinuing medications

that are no longer needed or may cause harm, which is a key strategy in geriatrics.

3. The Beers Criteria is primarily used for:

• Diagnosing dementia
• Monitoring renal function
• Identifying potentially inappropriate medications in older adults
• Screening for cardiovascular disease

Rationale: The Beers Criteria is a guideline that helps clinicians identify

medications that may pose more risks than benefits in older adults.

• Which pharmacokinetic change is commonly seen in older adults?
• Increased renal clearance
• Decreased hepatic metabolism
• Increased total body water
• Increased serum albumin 2 / 4

Rationale: Aging often reduces liver function, which can slow drug

metabolism, particularly for drugs processed by the cytochrome P450 system.

• Which class of medications is associated with a high risk of falls in the

elderly?

• Beta-blockers
• ACE inhibitors
• Benzodiazepines
• Statins

Rationale: Benzodiazepines can cause sedation, impaired balance, and

cognitive impairment, increasing fall risk.

• A 78-year-old patient with chronic kidney disease (CrCl 25 mL/min)

requires dosing adjustment for which of the following drugs?

• Loratadine
• Gabapentin
• Fentanyl patch
• Metoprolol

Rationale: Gabapentin is primarily renally excreted, and reduced renal

function necessitates a dose adjustment to prevent toxicity.

• / 4

• Which of the following vaccines is recommended annually for all adults

aged ≥65?

• Tdap
• Influenza

C. HPV

D. MMR

Rationale: Annual influenza vaccination is recommended for older adults

due to increased risk of severe influenza complications.

• In older adults, which of the following commonly contributes to adverse

drug reactions?

• Rapid metabolism of medications
• Decreased drug absorption
• Polypharmacy and altered pharmacokinetics
• Increased albumin levels

Rationale: Older adults are at higher risk of adverse drug reactions due to

multiple medications, reduced metabolism, and altered drug distribution.

• Which class of medications is considered first-line for the treatment of

neuropathic pain in older adults?

• Opioids
• NSAIDs
• / 4