Final Exam: NR 567 NR567 Latest

Final Exam: NR 567 / NR567 (Latest

Update 2025 / 2026) Advanced Pharmacology for the AGACNP | Questions & Answers | Grade A | 100% Correct – Chamberlain

Question:

Lithium vs valproic acid for management of bipolar disorder

Answer:

Valproic acid works faster and has better SE profile, but lithium is better at reducing SI risk and preventing relapse

Question:

lithium MOA

Answer:

Alters cation transport in nerve and muscle. May also influence reuptake of neurotransmitters.

• / 4

Question:

Lithium therapeutic range

Answer:

0.4-1.0 meq/L

Question:

Lithium toxicity range

Answer:

> 1.5 meq/L

Question:

Lithium toxicity manifestations

Answer:

LITHIUM: Lethargy, Increased urination, Tremor, Hypothyroid, Increased

thirst, Upset stomach, Muscle weakness

Question:

Lithium considerations for max effect

Answer:

Anti-manic effects begin 5-7 days after starting, may take up to 2+ weeks for max effect 2 / 4

Question:

Lithium - frequency of monitoring

Answer:

Initial: check every 2-3 days

Maintenance: check every 3-6 months

Question:

Lithium lab monitoring

Answer:

Renal function, T3, T4 and TSH before starting and then every 6 months

Question:

Lithium benefits

Answer:

May have neuroprotective features - promote neuronal growth and protect against atrophy

• / 4

Question:

Lithium - Patient teaching

Answer:

Drink 8-12 glasses of fluid per day Use aspirin for analgesia (avoid other NSAIDs)

Question:

valproic acid MOA

Answer:

increases levels of GABA - inhibitory neurotrans

Question:

valproic acid - monitoring

Answer:

Therapeutic range 50-125 mcg/L. Evaluate every 3-6 months Evaluate liver function baseline and periodically

• / 4