FREE LABORATORY SCIENCE AND STUDY GAMES ABOUT

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FREE LABORATORY SCIENCE AND STUDY GAMES ABOUT

MLT CH3 HEMOSTASIS EXAM QUESTIONS

Actual Qs and Ans Expert-Verified Explanation

This Exam contains:

-Guarantee passing score -58 Questions and Answers -format set of multiple-choice -Expert-Verified Explanation Question 1: a patient on warfarin therapy will be deficient in a functional amount of

Answer:

protein C and protein S

Question 2: a patient on therapeutic warfarin will most likely have a(n)

Answer:

increased PT/INR, increased aPTT, normal bleeding time, noral platelet count Question 3: The number of platelets an average megakaryocyte generates is approximately

Answer:

2000-4000

Question 4: if a physician suspects a qualitative platelet defect, the most useful test to order is the

Answer:

bleeding time

Question 5: reversal of a heparin overdose can be achieved by administration of

Answer:

protamine sulfate

Question 6: what describes protein C

Answer:

Vitamin K- dependent inhibitor to clotting

Question 7: the platelet parameter PDW refers to the

Answer:

variation in platelet cell size

Question 8: what are some causes of thrombocytopenia

Answer:

splenomegaly, chemotherapy, aplastic anemia Question 9: the size threshold range used by electrical impedance methods to count particles as platelets is

Answer:

2-20 fL

Question 10: the main regulatory protein of secondary hemostasis is

Answer:

antithrombin Question 11: A 3 year old had an aPTT drawn. He had to be restrained by several people to have the venipuncture. The result of the child's aPTT was 18.0 sec (ref range 22.0-38.0 sec). The aPTT controls were in range. What would account for the low aPTT result?

Answer:

the aPTT is invalid because of contamination with tissue factor Question 12: a phlebotomist drew a patient's blood for an aPTT at 10AM, but didn't bring it to the laboratory for testing until 4:30PM for testing. what would be the expected result?

Answer:

a falsely long aPTT is expected because some factors deteriorate rapidly at room temperature

Question 13: the activity of the lupus anticoagulant and anticardiolipin antibodies appears to be directed against

Answer:

phospholipid

Question 14: heparin inhibits clotting by

Answer:

enhancing the action of antithrombin Question 15: fibrin strands are cross-linked and the fibrin clot is stabilized by the activity of

Answer:

factor XIIIa Question 16: a microtainer EDTA sample is gotten from a fingerstick. It is run on an automated cell counter. platelet results are 178X10^9/L. the stained smear shows an average of 9 platelets per field under 1000X magnification. Based on this data you should

Answer:

report the results because the platelet count and platelet estimate correlate Question 17: a prolonged aPPT result is obtained on a patient diagnosed with acute disseminated intravascular coagulation (DIC). the patient has not yet been treated for this disorder. The most likely cause of the prolonged aPTT is

Answer:

systemic activation of the coagulation system depletes some factors more rapidly than the liver can synthesize them Question 18: which of the following is not a normal maturation stage for platelets?megakaryoblast; promegakaryocyte; micromegakaryocyte; megakaryocyte

Answer:

micromegakaryocyte Question 19: the hemorrhagic problems associated with scurvy are due to a deficiency of ___?___, which if a cofactor required for collagen synthesis

Answer:

Vitamin C

Question 20: a 30 year old female is admitted to the hospital with neurological symptoms.The following results are obtained:hemoglobin - 60g/L, hematocrit 0.19 L/L, platelet count 25X10^9/L, RBC morph - many schistocytes, ADAMTS-13 - markedly decreased. Diagnosis is?

Answer:

thrombotic thrombocytopenic purpura Question 21: the recommended type of microscopy for the performance of manual platelet counts is

Answer:

phase contrast

Question 22: what complexes are needed for blood coagulation to occur

Answer:

VIIa, tissue factor Ca2+, IXa, VIII, PF3, Xa, V Question 23: A sodium citrate tube is received in the lab for a PT and aPTT testing. results are: PT >100.0 seconds; aPTT >200.0 sec. on examination, a large clot is discovered. the abnormal test results are due to deficiencies of factors

Answer:

I, II, V, VIII,XIII

Question 24: con Willebrand factor is a

Answer:

plasma protein that binds platelets to exposed subendothelial collagen Question 25: A 25- year old male presents to his physician complaining of leg pain. the physician diagnoses a deep vein thrombosis and wants to determine the cause of the thrombotic episode what could be associated with such a throbotic episode

Answer:

Factor V Leiden and Prothrombin 20210 mutations, Lupus anticoagulant and anticardiolipin antibodies, and antithrombin and protein C deficiencies Question 26: measurement of the time required for fibrin formation when thrombin is added to plasma evaluates the

Answer:

fibrinogen concentration