NAU BIO 344 POSNER FINAL NEWEST ACTUAL

NAU BIO 344 POSNER FINAL NEWEST ACTUAL /

EXAM QUESTIONS AND ANSWERS VERIFIED/GRADED A+

Where would you NOT expect to find glycoproteins that contain

N-linked complex oligosaccharides: - ---Answers----proteins

found in the mitochondrial matrix

Ras is a monomeric GTPase (we will discuss Ras further in Chapter 15) that has intrinsic GTPase activity. This means that

it can intrinsically catalyze which of the following reactions: - -

--Answers----Ras-GTP --> Ras-GDP + P

Signal recognition particles (SRP) and SRP receptors are

involved in: - ---Answers----transport of ER signal

sequences from the cytosol to the rough ER

Signal recognition particles (SRP) and SRP receptors are: - --

-Answers----involved in co-translational translocation of polypeptide chains to the rough ER

The nucleotide triphosphates ATP and GTP are energetically

equivalent. This means that: - ---Answers----ATP + GDP -->

ADP + GTP ∆G = 0

The lipid that holds a 14 sugar oligosaccharide for transfer in

the formation of N-linked glycoproteins is:

-cholinesterase 1 / 3

-PI(3,4,5)P3

-Phospholipase C -IP3 - ---Answers----none of the choices

The process by which cells degrade their own components by enclosure in a membrane derived from the ER is termed - --- Answers----autophagy.

Receptors that are destined for degradation in lysosomes are

sequestered in: - ---Answers----intralumenal vesicles

Phospholipids in a cell are made: - ---Answers----on the

cytosolic side of the lipid bilayer of the ER

Nuclear localization sequences: - ---Answers----bind nuclear

import receptors in the cytosol

The removal of a phosphate group from NF-AT is catalyzed by:

• ---Answers----Calcineurin

LDL particles contain approximately 1500 molecules of: - ---

Answers----cholesterol

In the Golgi, Mannose-6-phosphate (M6P) is added to: - ---

Answers----lysosomal hydrolases

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Packaged inside a clathrin coated vesicle is a PI-5

phosphatase. The purpose of the PI-5 phosphatase is to: - ---

Answers----convert PI(4,5)P2 --> PI(4)P which results in the AP2 adaptin being released and the vesicle uncoating

The fusion of a late endosome with a lysosome forms a(n): - --

-Answers----endolysosome

Which is true about TOM? - ---Answers----It is needed to translocate all nuclear encoded proteins from the cytosol to the mitochondria.

The role of SAM is to - ---Answers----insert and fold proteins into beta barrels in the outer mitochondrial membrane.

A G-protein coupled receptor (GPCR): - ---Answers----is a 7-

pass transmembrane protein

Four types of intercellular signaling are: - ---Answers----

endocrine, synaptic, paracrine, contact dependent

If the α subunit of a trimeric G-protein has intrinsic GTPase

activity . This means: - ---Answers----it can catalyze the

hydrolysis reaction that converts bound GTP to bound GDP

Which of the following are amino acids whose side chains can be phosphorylated by specific protein kinases. - ---Answers-- --Threonine, Tyrosine and Serine

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