NCLEX PATHO QUESTIONS - EXAM 1
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Ale The plasma membrane in human cells is comprised of:
- A single layer of phospholipids and proteins
- A capsid made up of lipids and polysaccharides
- A phopholipid bilayer including cholesterol and proteins
- Cellulose
C
The primary function of the mitochondria is:
- Catalyze protein translation
- Package proteins for transport
- Manufacture of ATP
- Management of genetic material
C Chronic hypertension requires that the heart pumps harder with each contraction. This means that the left ventricle experiences more stretch
than usual. This can result in ________ of the cells of the ventricle:
- Metaplasia
- Dysplasia
- Atrophy
- Hypertrophy
D
Flipases and flopases are enzymes involved in the asymmetry of the cell membrane. Which of these is a function of membrane asymmetry?
- Marking the cell for apoptosis
- Allows for selective permeability of the membrane
- Manufacture of integral proteins
- Involved in endocytosis of nutrients
- Metaplasia
- Dysplasia
- Atrophy
- Hypertrophy
- Aquaporins
- Actins
- Bradykinins
- Histamines
- Thiamine pyrophosphate
- Angiotensin converting enzyme
- Carbonic anhydrase
- Glucose-6-phosphate
- Osmosis
- Filtration
- Active transport
- Magic
A Mr. Pasteur had his arm in a cast for six weeks. After the cast was removed, his arm was noticeably smaller. This is an example of:
C In diabetes inspidus, patients excrete a large volume of dilute urine. Diabetes inspidus is a disease involving the mutation of proteins that are involved in the movement of water in and out of the cell. What are these proteins?
A Which of the following is the body's primary buffer in the blood and the kidneys?
C Starling's forces are forces involved in the movement of fluid, secondary to the effects of:
B
Keith Richards presented into the emergency department because of swelling in his legs, a process known as edema. He has a history of liver failure, and as a result has a decreased capacity to produce proteins such as albumin. The edema is likely a result of:
- Increased oncotic pressure in the capillary
- Decreased capillary permeability
- Decreased oncotic pressure in the capillary
- A build-up of cytotoxins from the liver
- No dissociation in water
- Complete dissociation in water
- No reaction in water
- Become proton acceptors in water
C According to the Br∅nsted-Lowry acid-base theory, the following is a characteristic of a strong acid.
B
Opsonization is a process by which:
- Mast cells are degranulated to release histamine
- Antigens are identified by special protein tags
- Collagen is exposed, allowing for platelet interaction
- Proteins bind to antigens to negate the negative charge, allowing for phagocytic interactions
- A reaction to endotoxins produced by antigens
- A binding to the mannose residues on antigens
- The breakdown of fibrinogen
- The activation of antibodies
B Activation of complement is one of the responses of the innate immune system. The classic pathway is a response to:
D
The first phagocytic cells to respond to exposure to an antigen are the:
- Neutrophils
- Monocytes
- Macrophages
- Eosinophils
A
This is an example of an endothelial-derived antimicrobial peptide:
- Lectin
- Complement
- Interleukin
- Defensin
D A patient you are taking care of requires a blood transfusion of red blood cells. You know that all of the following are true about red blood cells
EXCEPT:
- They carry oxygen to the cells and tissues of the body
- They contain multiple nuclei to aid in replication in the bloodstream
- They release nitric oxide to help relax constricted blood vessels
- They are biconcave in shape in order to increase their surface area
- Erythrocyte
- Leukocyte
- Platelet
- Beta-globulin
B This component of the hematologic system is a disc-shaped cytoplasmic fragment that can change its shape from a sphere to that containing pseudopods. It is active in the formation of clots and contains dense granules that can secrete ADP, serotonin and thromboxane.
C
Polycythemia Vera is a disease process in which the bone marrow:
- Isn't making any red blood cells
- Isn't making any platelets
- Is making too many red blood cells
- Is making too many platelets
C A patient has been on your telemetry unit because of a diagnosis of chest pain and has been on heparin. On the third day of admission they have a very low platelet count, less than 100,000 (normal is 150,000 - 450,000). They have patches of purple like lesions called purpura and bled
from their guns while brushing their teeth. The name for this disease is:
- Thrombocytopenia
- Polycythemia Vera
- Mononucleosis
- Creutzfeldt-Jakob disease
A