NOT ENOUGH ANTIDIURETIC HORMONE, NOT ABLE TO HOLD ONTO THEIR URINE

NUR 304 DRUGS

• Diabetes insipidus

Answer has to do w/ADH AND PEE

NOT ENOUGH ANTIDIURETIC HORMONE, NOT ABLE TO HOLD ONTO THEIR URINE

• Vasopressin (Pitressin) ACTION

Answer Synthetic ADH that acts on kidneys to in- crease water reabsorption

• Vasopressin (Pitressin) CONTRAINDICATIONS

Answer Patients w/

-renal failure

(WE NEED IT TO WORK ON KIDNEYS)

-CVD, Heart failure

(BC WE WANT PATIENTSTO HOLD ONTOWATER, HEARTWILL HAVE TO WORK

HARDER)

• Vasopressin (Pitressin) ADVERSE EFFECTS

Answer WHHAN

-Water intoxication -Headache -Hypertension -Abdominal pain -Nausea

• Vasopressin (Pitressin) DRUG INTERACTIONS 1 / 4

DECREASED

-heparin -liththium -alcohol -phenytoin

INCREASED ANTIDIURETIC EFFECT

Answer Carbamazepine, TCA antidepressants

• Vasopressin (Pitressin) MONITOR

Answer -vs

-I&O -Electrolytes -urine (specific gravty) -AVOID alcohol -No excessive amounts of h2o

• Anti-thyroid medication

Answer Propylthiouracil (PTU) &

Radioactive Iodine Iodine 131

• Propylthiouracil (PTU) ACTION

Answer Interferes with thyroid hormone synthesis

-cant form their t3 & t4

• Propylthiouracil (PTU)

Answer 2 / 4

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GRAVES DISEASE, NEEDS FREQUENT LABS

-& other forms of hyperthyroidism

• Iodine 131

Answer Isotope created by iodine and is attracted to thyroid gland radiates thyroid gland, partial or complete obstruction of thyroid gland (takes 1-3 months. Max benefits 3-6 months)

• Propylthiouracil (PTU) CONTRAINDICATIONS

Answer

• Preg Cat X

• dont give to breast feeding pts.

• Propylthiouracil (PTU) ADVERSE EFFECTS

Answer

• agranualcytosis - low wbc (monitor CBC)

• may have rash
• lost of taste

• PTU anti-thyroid drug NURSING CARE

Answer PTU

Answer

• can develop agranulocytosis may appear 4-8 weeks after treatment. (Infection due to low wbc)

-can have metalic taste in mouth and increase salivation

• Iodine I-131 PT TEACHING

Answer 3 / 4

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• pt is radioactive after therapy for a few days

• limit close contact, no more than 30 min a day
• cant be around children or pregnant women after therapy
• women who come in contact cant get pregnant after 1 year
• double flush urine

• Hypothyroidism drug

Answer Levothyroxine (Synthroid, Levothroid)

• Levothyroxine (Synthroid, Levothroid) ACTION

Answer Synthetic for of t4

• Levothyroxine (Synthroid, Levothroid) ADRS

Answer -NO ADRS if used correctly

-If dose is high = hyperthyroidism

• Levothyroxine (Synthroid, Levothroid) PRECAUTIONS

Answer Older patients start on lower dose due to cardiac stimulation

-they are more sensitive

• Levothyroxine (Synthroid, Levothroid) INTERACTIONS

Answer -Any drugs that ef- fect absorption (antacids, iron, BSAs)

-warfarin (increase anticoagulant effects) -anti-diabetic agents (increase insulin requirements) -Digoxin levels (may have to reduce its dosing)

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