NR566 NR 566 Final Exam

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NR566 / NR 566 Final Exam Advanced Pharmacology for Care of the Family Expected Questions and Answers

• Why do men have higher hematocrit levels than women?

Ans>> They produce more testosterone which results in higher amounts of erythropoietin and erythrocytes.

• What is the Black Box warning for the androgen Oxandrolone?

Ans>> Can cause peliosis hepatitis; blood-filled cysts form in the liver leading to failure or intrabdominal hemorrhage

• What are the disorders that the androgen testosterone can treat?

Ans>> Hypogo- nadism (male), replacement therapy 1 / 4

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• What are the disorders that the androgen methyltestosterone can treat?

Ans>> - Replacement and hypogonadism in males

• What are the disorders that the androgen oxandrolone can treat?

Ans>> Catabolic states (cachexia)

• Testosterone can be used to treat what symptoms in post-menopausal women?

Ans>> Reduced genital sensitivity, fatigue, and decreased libido

• What hormones does androgens suppress?

Ans>> Luteinizing and follicle-stimulat- ing

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• Which particle in the life cycle of chlamydia trachomatis is considered

infectious and first infects the host cell?Ans>> elementary body

• What is the recommended testing for males suspected to have Chlamydia?-

Ans>> first-catch urine for nucleic acid amplification test (NAAT)

• What are the CDC screening recommendations for chlamydia in asympto- matic

females?Ans>> annual screening annually in sexually active females 24 years or younger.

• What is the recommend treatment for uncomplicated chlamydia in

non-pregnant females and males?Ans>> doxycycline 100mg by mouth twice daily x7 days (alternate azithromycin 1g by mouth x1)

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• What is the mechanism of action of donepezil (Aricept)?

Ans>> inhibits centrally active acetylcholinesterase

• What are the common side effects of Aricept?

Ans>> gastrointestinal symptoms (nausea and diarrhea), headache, dizziness, muscle weakness

• List the precautions for Aricept?

Ans>> sick sinus syndrome and seizure disorder

• When combined with

and peripheral side effects and rate of elimination can be increased for Aricept?Ans>> CYP2D6 & CYP3A4

• What is the mechanism of action of Rivastigmine (Exelon)?
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