NURS 180 - PRESENTATION NCLEX

NURS 180 - PRESENTATION NCLEX

QUESTIONS AND ANSWERS WITH

VERIFIED SOLUTIONS 100% CORRECT

RATED A+

A nurse is reviewing a client’s current medications before starting IV imipenem-cilastatin for an infection. Which concurrent medication raises concern for a drug interaction?

• Regular insulin
• Furosemide
• Valproic acid
• Ferrous sulfate

✔ Answer: C. Valproic acid

Explanation: Imipenem-cilastatin can reduce the effectiveness of valproic acid, a medication used to control seizures. This interaction may increase the risk of seizure activity. If both drugs must be administered together, close monitoring for seizure symptoms is essential.

To allow imipenem to effectively reach infected tissues, which enzyme must be inhibited?

• Vitamin D receptor
• DHP-1 (Renal dehydropeptidase I)
• DHP-2 (Renal dehydropeptidase II)

D. SYSR-1

✔ Answer: B. DHP-1

Explanation: DHP-1 breaks down imipenem in the kidneys, which reduces its

effectiveness. Cilastatin is combined with imipenem to inhibit DHP-1, ensuring higher concentrations of the antibiotic reach the tissues..

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A patient is taking vancomycin, what is of greatest concern?

• "I will take my full prescription, even though I feel better."
• "I will take my allergy medicine in the morning."
• "I will stay away from drugs that can further harm my kidneys."
• "I'm taking vancomycin to help the infection in the intestines." -

ANSWER✔✔B. "I will take my allergy medicine in the morning."

Rationale - Antihistamines are contraindicated for vancomycin

When taking vancomycin, which of the following is NOT an adverse effect?

• Ototoxicity
• Nephrotoxicity
• GI discomfort
• Sun sensitivity - ANSWER✔✔D. Sun sensitivity

Rationale - Vancomycin does not cause sun sensitivity

A client who is allergic to penicillin is at an increased risk for an allergy to which drug?

A: Cefoxitin Sodium

B: Cefadroxil

C: Cefazolin Sodium

D: Cefotaxime - ANSWER✔✔C. Cefazolin Sodium

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