PATHO 370 MIDTERM EXAM NEWEST ACTUAL

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PATHO 370 MIDTERM EXAM NEWEST ACTUAL

EXAM TEST BANK 250 QUESTIONS AND CORRECT

DETAILED ANSWERS (VERIFIED ANSWERS )

|ALREADY GRADED A+

Transfusion reactions involve RBC destruction caused by

• donor antigens
• recipient antibodies
• donor T-cells
• recipient T cells - ANSWER- b

The activated partial thromboplastin time (aPTT) is a measure of the integrity of - ANSWER- the intrinsic pathway

A 5-year-old patient's parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk as a result of pain. The child's most likely diagnosis is - ANSWER- ALL (acute lymphoid leukemia)

Patients who experience anemic episodes when exposed to certain drugs most likely have - ANSWER- glucose-6-phosphate dehydrogenase deficiency

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An important mediator of a type I hypersensitivity reaction is - ANSWER- histamine

A newborn has melena, bleeding from the umbilicus, and hematuria. The newborn most likely experiencing - ANSWER- vitamin K deficiency bleeding.

The patient is a 12-year-old boy diagnosed with acute lymphoid leukemia (ALL). As part of treatment, the patient must undergo several weeks of chemotherapy. The most serious complication of chemotherapy is - ANSWER- infection

A child with a history of recent strep throat infection develops glomerulonephritis. This is most likely a type _____ hypersensitivity reaction. - ANSWER- III

Widespread activation of the clotting cascade secondary to massive trauma is called

• hemophilia B

.b. disseminated intravascular coagulation (DIC).

• Hageman disease.
• idiopathic thrombocytopenia purpura. - ANSWER- b

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia? - ANSWER- iron deficiency 2 / 4

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When systemic vascular resistance is decreased, blood flow - ANSWER- decrease

The only known curative treatment for CML is allogeneic bone marrow transplantation from a suitable donor.

true or false? - ANSWER- true

The primary source of erythropoietin is provided by the - ANSWER- kidney

Dysfunction of which organ would lead to clotting factor deficiency? - ANSWER- liver

Disseminated intravascular coagulation may be treated with heparin therapy to - ANSWER- inhibit clotting factor consumption.

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions, because

• massive histamine release from mast cells leads to vasodilation.
• toxins released into the blood interfere with cardiac function.
• anaphylaxis results in large volume losses secondary to sweating. 3 / 4

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• hypoxia resulting from bronchoconstriction impairs cardiac function. -

ANSWER- a

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called - ANSWER- bcr-abl

Which disorder is associated with a type III hypersensitivity mechanism of injury? - ANSWER- Systemic lupus erythematosus

The cause of the most common form of anemia is - ANSWER- iron deficiency

The principle Ig mediator of type I hypersensitivity reactions is - ANSWER- IgE

Which group of clinical findings describes the typical presentation of ALL (acute lymphoid leukemia)? - ANSWER- Pain in long bones, infection, fever, bruising

The major cause of death from leukemic disease is - ANSWER- infection

Renal insufficiency is a common complication of which disease? - ANSWER- myeloma

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