PCBl 3233l Examl 2l Latestl 2026l 2027l

PCBl 3233l Examl 2l ( l 2026/l 2027l Update)l Review l l l Questionsl &l Answersl l Gradel A

Q:l Whatl arel yourl proinflammatoryl cytokines?

Answer:

-IL-1Beta -IL-6 -CXCL8l (IL-8)

-IL-12

-TNFl Alpha

Q:l Whatl doesl TLR7l Recognize?

Answer:

-Ligand:l Singlel strandedl virall RNA

-Detectsl RNAl virusesl -Carriedl byl dendriticl cells,l NKl cells,l eosinophils,l &l B-cells

Q:l Whatl doesl TLR5l recognize?

Answer:

-Ligandl isl Flagellin -Foundl inl plasmal membranel -Carriedl byl intestinall &l epitheliall cells

Q:l Whatl doesl TLR3l recognize?

Answer: 1 / 3

-Ligand:l Doublel strandedl virall RNA

-Carriedl byl NKl cells

Q:l Whatl doesl TLR4l recognize?

Answer:

-LPS -Recognizesl graml negativel bacteria -Carriedl byl macrophages,l mastl cells,l dendriticl cellsl &l eosinophils

Q:l Whatl isl thel adaptorl proteinl forl TLRl signaling?

Answer:

MyD88

Q:l Functionl ofl IL-6?

Answer:

Actsl onl musclel tol increasel temperature

Q:l Functionl ofl IL-1Beta

Answer:

Worksl w/TNF-Al tol activatel endotheliall cellsl &l inducel inflammation

Q:l Functionl ofl IL=2?

Answer:

Activatesl NKl Cells

Q:l Whatl doesl NODl 1l do? 2 / 3

Answer:

Recognizesl graml (-)l peptidoglycan

Q:l Whatl doesl NOD-2l do?

Answer:

Recognizesl muramyll dipeptide

Q:l Whatl arel NOD-likel receptors?

Answer:

Receptorsl inl thel cytoplasml thatl recognizel pathogens

Q:l Wherel dol monocytesl mature?

Answer:

Infectedl tissue

Q:l Whatl isl anotherl namel forl neutrophils?

Answer:

Polymorphonuclearl Leukocytes

Q:l Selectinsl are

Answer:

-carbohydrate-bindingl lectin -P,l E,l &l Ll selectins

Q:l Integrinsl bindl to

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