Pharmacology Chapter 2: NCLEX Questions

Pharmacology Chapter 2: NCLEX Questions

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• What is the study of the physiochemical properties of

drugs and how they influence the body called?

• Pharmacokinetics
• Pharmacotherapeutics
• Pharmacodynamics
• Pharmacology
• Pharmacodynamics
• Pharmacokinetics involves the study of
• physiologic interactions of drugs.
• distribution rates among various body compartments.
• interactions between various drugs.
• adverse reactions to medications.
• distribution rates among various body compartments.

• What is an alternate name for biotransformation of a

drug?

• Absorption
• Dilution
• Excretion
• Metabolism
• Metabolism
• A drug given by which route is altered by the first-pass

effect?

• Sublingual
• Subcutaneous
• Oral
• Intravenous
• Oral
• Drug half-life is defined as the amount of time required

for 50% of a drug to

• be absorbed by the body.
• exert a response.
• be eliminated by the body.
• reach a therapeutic level.
• be eliminated by the body.
• Which action, when performed by the nurse, will

increase the absorption of a medication administered intramuscularly?

• Applying cold packs to the injection site
• Lowering the extremity below the level of the heart
• Administering the medication via the Z-track method
• Massaging the site after injection
• Massaging the site after injection

• Highly protein-bound drugs
• increase the risk of drug-drug interactions.
• typically provide a short duration of action.
• must be administered with 8 ounces of water.
• have a decreased effect in patients with a low albumin

level.

• increase the risk of drug-drug interactions.
• To achieve the most rapid onset of action, the health

care provider will prescribe the medication to be administered by which route?

• Subcutaneously
• Intravenously
• Intramuscularly
• Intrathecally
• Intravenously
• Patients with renal failure would most likely have

problems with drug

• excretion.
• absorption.
• metabolism.
• distribution.
• excretion.
• What is the ratio between a drug's therapeutic effects

and toxic effects called?

• Tolerance
• Cumulative effect
• Therapeutic index
• Affinity
• Therapeutic index

• When a patient asks the nurse why a lower dose of

intravenous pain medication is being given than the previous oral dose, what knowledge will the nurse draw on to respond to the patient?

• Medications given intravenously are not affected by

the first-pass effect.

• Medications given orally bypass the portal circulatory

system.

• A large percentage of an intravenously administered

drug is metabolized into inactive metabolites in the liver.

• Drugs administered intravenously enter the portal

system prior to systemic distribution.

• Medications given intravenously are not affected by the first-pass effect.
• The nurse understands that drugs exert their actions

on the body by (Select all that apply.)

• interacting with receptors.
• making the cell perform a new function.
• inhibiting the action of a specific enzyme.
• altering metabolic chemical processes.
• interacting with receptors.
• inhibiting the action of a specific enzyme.
• altering metabolic chemical processes.
• The nurse needs to be aware that which factors will

affect the absorption of orally administered medications?(Select all that apply.)

• Presence of food in the stomach
• pH of the stomach
• Patient position upon intake of medication
• Form of drug preparation
• Time of day
• Presence of food in the stomach
• pH of the stomach
• Form of drug preparation
• Time of day
• An elderly woman took a prescription medicine to

help her to sleep; however, she felt restless all night and did not sleep at all. The nurse recognizes that this woman has experienced which type of reaction or effect?a Allergic reaction b Idiosyncratic reaction c Mutagenic effect d Synergistic effect b Idiosyncratic reaction