Pharmacology Final: NCLEX style practice

Pharmacology Final: NCLEX style practice

questions Leave the first rating Terms in this set (67) Science Medicine Save Which characteristics may allow a drug to cross the blood-brain barrier? Select all that apply

• The drug is lipid-soluble
• The drug has a transport system
• The drug is available for IV admin
• The drug is metabolized by the

CNS A, B The Nurse understands that when administering drug therapy to older clients there are normal age-related absorption changes. How is absorption affected in the older client? Select all that apply

• Decreased glomerular function
• Decreased blood flow
• Decreased absorption surface
• Decreased GI motility
• Increased gastric pH

B, C, D, E

The nurse understands that normal age-related changes occur with drug administration, and drugs that are excreted by the kidney may have to be given in smaller doses. What are the normal age-related changes in excretion of drugs? Select all that apply

• Decreased renal blood flow
• Decreased glomerular function
• Decreased hepatic blood flow
• Decreased tubular secretion
• Decreased serum albumin

A, B, D

The nurse administers an IV medication with a half-life of 24hrs.The nurse should recognize that what factors in this client that could extend the drug's half life? Select all that apply

• Gastrointestinal disease
• Kidney disease
• Liver disease
• Cardiovascular disease
• Route of administration

B, C, D

How would the dosage of a partly protein-bound drug be altered if another drug having a higher attraction to albumin than the first drug is administered?

• The dosage of the first drug may

have to be decreased

• The dosages of both the first and

the second drugs should be reduced equally

• The dosage of the first drug may

have to be increased

• The dosage of the second drug

may have to be increased A The nurse has administered a drug that is known to be lipid soluble. The drug's solubility will primarily affect what aspect of pharmacokinetics?

• Absorption of the drug
• Metabolism of the drug
• Excretion of the drug
• Distribution of the drug

D The nurse administers a specific medication to an older adult client every 4 hours. THe client has a history of chronic renal failure. The nurse should assess for indications

of:

• Cumulative drug effects
• Drug-drug interactions
• Impaired absorption
• Drug tolerance

A

A nurse is administering drugs to a 70 year old patient who has a reduced plasma albumin level. When assessing the patient for therapeutic outcomes of drug therapy, the nurse

will also be careful to observe for:

• Possible drug toxicity
• Decreased therapeutic effects
• Altered drug absorption
• Increased drug metabolism

A The nurse should consider teratogenic effects when caring for what clients? Select all that apply

• An 88 year old client with CHF

and PE

• A 51 year old client who is

immunocompromised following bone marrow transplant

• A 54 year old client being treated

in the intensive care unit for multi organ dysfunction syndrome

• A 29 year old client receiving

prenatal care in her first trimester of pregnancy

• A 37 year old client who is taking

fertility drugs D, E The breakdown of oral drugs in the liver immediately after absorption is known as which of the following?

• Distribution
• First-pass effect
• Enzyme induction
• Passive diffusion

B