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Week 2 Midterm Exam: NR546 / NR-
546 ( Update 2025 / 2026) Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner Questions and Answers - Chamberlain
Question:
What are transcription factors?
Answer:
turn the gene expression on or off
Question:
What are signal transduction cascades?
Answer:
the process through which cells communicate (controlled by a signaling cascade such as the g-linked protein system)
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Question:
What is the role of g-linked protein systems? What are they triggered by?
Answer:
Think of them as an operator: pass on the message from one receptor to
another; triggered by neurotransmitters
Question:
Most common action of psychotropic drugs
Answer:
modify the action of the g-liked protein system which occurs in a spectrum:
- No agonist: not "plugged in" but still produces a detectable output signal
+Agonist: messenger acts at its greatest potential
* Antagonists: blocks an agonist that may be overstimulating the NTM
(considered silent and is the cause of SE in medications)
- partial agonists: considered "stabilizers" and help maintain balance
*Inverse agonists: deactivate the g-linked messenger system; totally inactive;
reduction in transduction
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