Week 3 Midterm Exam: NR546 NR-

Week 3 Midterm Exam: NR546 / NR-

546 (Latest 2025 / 2026) Advanced Pharmacology Psychopharmacology for the PMHNP | Questions and Answers | 100% Correct | Grade A - Chamberlain

Question:

How does serotonin levels change as we age

Answer:

it decreases normally with age

Question:

What section of the brain is effected if a client cannot copy a written word or drawing

Answer:

parietal lobe

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Question:

Define neuroplasticity

Answer:

The brain's ability to reorganize itself by forming new neural connections and pathways to fully benefit from the altered neurotransmitter levels

Question:

Cause of positive symptoms in schizophrenia

Answer:

hyperactivity of dopamine in the mesolimbic pathway

Question:

cause of negative symptoms of schizophrenia

Answer:

hypoactivity of dopamine in the mesocortical prefrontal cortex and nucleus accumbens

Question:

Which patients are twice as likely to develop TD with chronic use of Conventional ATP

Answer:

those who develop EPS early in treatment 2 / 4

Question:

Why do you begin with monotherapy for antipsychotics

Answer:

because the use of multiple antipsychotics can increase the risk of QT prolongation

Question:

Special considerations for pregnancy with antipsychotic

Answer:

• risk of w/d symptom in the newborn (EPS may be present at delivery)
• atypical atp more harmful than typical atp due to increased risk of

gestational metabolic complication, increased gestational age weight, and increased birth weight. Avoid clozapine, ziprasidone, olanzapine, risperidone and quetiapine in pregnancy especially third trimester

Question:

Breast feeding instruction with ATP

Answer:

all atp are assumed to be secreted in breast milk, it is recommended that either the drug is discontinued or the infant bottle feeds

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Question:

What atp should be avoided in elderly and why

Answer:

Avoid the use of haloperidol, ziprasidone, and olanzapine due to an increased risk of cerebrovascular accident (CVA), cognitive decline, and death in persons with dementia and with dementia-related psychosis.

Question:

Black box warnings Aripiprazole in children

Answer:

Increased risk of suicide in children.

Question:

What substances can mimic positive symptoms of paranoid schizophrenia

Answer:

High and repeated doses of amphetamines or cocaine

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